Interdisziplinäres Forschungszentrum Ostseeraum (IFZO)


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Understanding receptor-ligand interactions at a molecular level; Implications for immune responses

Fokus: GESUNDHEIT & LEBEN

The immunogenicity of a biomolecule, and particularly how T cell receptors or NK cell receptors interact with human leukocyte antigens (HLA) presenting specific epitopes, is profoundly shaped by its structural characteristics. Understanding the relationship between molecular structure and dynamics of interactions should allow us to assess and predict the immunogenic potential of HLA-restricted peptides. By integrating structural and dynamic data with immunological outcomes, we aim to bridge the gap between molecular design and immune function.

Adnane Achour holds a Bachelor of Science degree in biophysical chemistry and a Master of Science in chemical engineering. He further advanced his academic career by earning a PhD in molecular immunology. Currently, he serves as a professor of molecular immunology, sharing his expertise and conducting research in this specialized field.

Moderation: Professorin Dr. Mihaela Delcea

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Prof. Dr. Dr. h.c. Michael North
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Dr. Alexander Drost
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D-17487 Greifswald
Tel.: +49 (0)3834 420-3341/-3309
Fax: +49 (0)3834 420-3333
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Understanding receptor-ligand interactions at a molecular level; Implications for immune responses

Fokus: GESUNDHEIT & LEBEN

The immunogenicity of a biomolecule, and particularly how T cell receptors or NK cell receptors interact with human leukocyte antigens (HLA) presenting specific epitopes, is profoundly shaped by its structural characteristics. Understanding the relationship between molecular structure and dynamics of interactions should allow us to assess and predict the immunogenic potential of HLA-restricted peptides. By integrating structural and dynamic data with immunological outcomes, we aim to bridge the gap between molecular design and immune function.

Adnane Achour holds a Bachelor of Science degree in biophysical chemistry and a Master of Science in chemical engineering. He further advanced his academic career by earning a PhD in molecular immunology. Currently, he serves as a professor of molecular immunology, sharing his expertise and conducting research in this specialized field.

Moderation: Professorin Dr. Mihaela Delcea

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